Image Reconstruction

Applications of variational principles and deep learning to image reconstruction.

Image reconstruction is a fundamental inverse problem arising across diverse scientific and engineering domains — from medical imaging and remote sensing to computational photography. Given incomplete, noisy, or indirectly observed measurements, the goal is to recover the underlying image faithfully. We develop robust variational models and efficient algorithms to address challenging reconstruction problems, with an emphasis on theoretical guarantees and practical performance.


Tomographic Reconstruction

Tomographic reconstruction aims at recovering the internal structure of an object from a collection of projected measurements taken at different angles. The problem is inherently ill-posed. We develop variational and deep learning models that incorporate prior knowledge of the underlying structure to achieve high-quality reconstruction from limited and possibly dynamical data.

Real-time MRI-guided brain intervention based on deep unrolled neural network.
Proposed non-negative INR factorization model for dynamic PET reconstruction.
Robust dynamic SPECT reconstruction with scarce angular and limited temporal sampling using Deep Spatial Prior with Continuous Temporal Representation.

References

(He et al., 2023) (Zhang et al., 2025) (Wu et al., 2026)


References

2026

  1. Robust Dynamic SPECT Reconstruction with Scarce Angular and Limited Temporal Sampling
    Yicheng Wu, Roy He, Qiaoqiao Ding, Xiaoqun Zhang, and Chao Wang
    2026

2025

  1. Dynamic PET Image Reconstruction via Non-Negative INR Factorization
    Chaozhi Zhang, Wenxiang Ding, Roy Y He, Xiaoqun Zhang, and Qiaoqiao Ding
    SIAM Journal on Imaging Sciences, 2025

2023

  1. A deep unrolled neural network for real-time MRI-guided brain intervention
    Zhao He, Ya-Nan Zhu, Yu Chen, Yi Chen, Yuchen He, Yuhao Sun, Tao Wang, Chengcheng Zhang, Bomin Sun, Fuhua Yan, and others
    Nature Communications, 2023